Prof Galassi was coinvestigators of the following research projects at the Division of Cardiology, Department of Internal Medicine and Systemic Disease of the University of Catania.

2003-2007. Principal Investigator in the FINESSE trial (Facilitated Intervention with Enhanced reperfusion Speed to Stop Events).
This is a multicenter randomized double blind placebo controlled trial for patients presenting with ST segment elevation myocardial infarction. The objective of the trial is to demonstrate that rapid administration of aspirin abciximab, reteplase, and heparin followed by early catheterization and intervention, when not controindicated, is superior to the administration of aspirin and heparin followed by diagnostic angiography and primary intervention with abciximab after angiography when not controindicated.

2008-2011 Principal Investigator of the IRCTO (Italian Registry on Chronic Total Occlusion).
This is a observational Registry executed among 61 italians centers whose objective was that of assessing prospectively the prevalence, therapeutic choices, and short and mid-term prognosis (up to 3 years) of patients with angiographic evidence of a chronic total occlusion in a major coronary artery.

2008-2011 Study Coordinator of the ERCTO (European Registry on Chronic Total Occlusion).
This is a observational web based registry executed among 32 european operators whose objective was that of assessing retrospectively patients with angiographic evidence of a chronic total occlusion in a major coronary artery, who underwent revascularization by coronary angioplasty: percentage of revascularization success, techniques of choice, and short and mid-term prognosis (up to 3 years) are going to be evaluated in this registry.

2011-2014 Principal Investigator in the Board of Steering Committee of the EURO CTO Trial
(A Randomized Multicentre Trial to Evaluate the Utilization of Revascularization or Optimal Medical Therapy for the Treatment of Chronic Total Coronary Occlusions). This is a randomized study, executed by expert CTO operators around Europe, who assess the efficacy and safety of percutaneous revascularization for chronic total coronary occlusions (CTO) in comparison to medical therapy in patients with coronary artery disease and stable angina pectoris.


The web-based registry ERCTO (


Principal investigator and coordinator:

Head of Cardiac Catheterization and Interventional Cardiology Unit
University of Catania, Ferrarotto Hospital, Catania, Italy

Board of Directors:

Gerald S. Werner  MD, FACC, FESC, FSCAI
Medizinische Klinik, Klinikum Darmstadt, Germany

N Reifart, MD, FESC, FACC,  RANS
Main Taunus Kliniken, Bad Soden, Germany

Javier Escaned, MD, PhD, FESC
Cardiovascular Institute, Hospital Clinico San Carlos, Madrid, Spain

Carlo Di Mario, MD
National Heart and Lung, Institute Imperial College, London, UK

Hans Bonnier, MD
Dep. of Cardiology, Interventional Cardiology, Universitair Ziekenhuis Brussel


Research Assistants:

SD Tomasello MD, Research Fellow, Clinical Division of Cardiology, Ferrarotto Hospital , Catania , Italy

Francesco Marzà MD, Postgraduate School of Cardiovascular Diseases, University of Catania, Catania, Italy


Last year of observation:   2013

Doctor Center Patient count Operation
Werner Gerald S. Medizinische Klinik I Klinikum Darmstadt 193 194
Büttner Heinz Joachim Herz-Zentrum Bad Krozingen 169 177
Avran Alexandre Clinique de Marignane et HP Clairval, Marseille 136 136
Boudou Nicolas Rangueil university hospital 117 117
Galassi Alfredo R. Cannizzaro Hosp, Univ of Catania Italy 109 114
Spratt James C. Forth Valley Acute Hospitals 106 106
Meyer-Geßner Markus Augusta-Krankenhaus, Düsseldorf 89 98
Mashayekhi Kambis HELIOS Vogtland-Klinikum Plauen 94 94
Reifart Nicolaus Main Taunus Kliniken - Bad Soden, Germany 92 92
Christiansen Evald Høj Skejby University Hospital 77 77
Goktekin Omer Eskisehir Osmangazi University 72 72
Aigars Lismanis Pauls Stradins Clinical University Hospital 69 70
Bufe Alexander Kardiologie HELIOS Klinikum 69 69
Serra Antonio Hospital del Mar 64 64
Bryniarski Leszek Jagiellonian University Medical College 62 62
Garbo Roberto Ospedale San Giovanni Bosco 58 58
Victoria Martin Hospital de la Santa Cruz y San Pablo 57 58
Artis Kalnins Riga East Clinical University Hospital 50 54
Gagnor Andrea Ospedale degli Infermi 53 53
Carlino Mauro San Raffaele Hospital 46 51
Isaaz Karl University of Saint Etienne 51 51
Grancini Luca Centro Cardiologico Monzino, Milan 50 50
Pieper Michael Herzzentrum Bodensee 50 50
Hildick-Smith David Brighton and Sussex University Hospitals 47 47
Sardella Gennaro Policlinico Umberto I Sapienza University of Rome 42 42
Schulze Ralph Herzklinik Ulm Dr. Haerer und Partner 30 39
Weilenmann Daniel Kantonsspital, St. Gallen 36 37
DiMario Carlo National Heart and Lung Institute 36 36
Wójcik Jarosław Medical University of Lublin 36 36
Lefevre Thierry Institut Hospitalier Jacques Cartier 33 33
Lauer Bernward Zenrtalklinik Bad Berka 29 29
Gürmen A. Tevfik University of Istanbul 28 28
George Sianos Panorama Thessaloniki 26 27
Barbato Emanuele Cardiovascular Center Aalst OLV Clinic - Aalst (Belgium) 26 26
Kulekci Kemal Heart Center Gorinchem, Dordrecht 22 22
Escaned Javier Hospital Clinico San Carlos 18 18
Louvard Yves Institut Hospitalier Jacques Cartier 16 17
Elhadad Simon CH LAGNY Sur Marne 16 16
Javier Goicolea Madrid Invasive Cardiology Hospital 11 11
Sievert Horst CardioVasculäres Centrum 9 9
Koolen Jacques Catharina Hospital 8 8
Gershlick Anthony University of Leicester 6 6
Erglis Andrejs Pauls Stradins Clinical University Hospital 3 3
Dr. Test Test center 2 2
Strange Julian Bristol Heart Institute, Bristol, UK 1 1
Dobri Hazarbassanov St Anna University Hospital 1 1
Thuesen Leif Aarhus University Hospital 1 1

Statistical Analysis

47 European interventionalists have participated in the Registry. They were selected on the basis of more than 2416 CTO PCI uploaded during the year 2013.

Total number of enrolled patients: 2462

For browsing previous years of observation please go to:


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